LIPOMA

Posted Mon, 04/27/2009 - 06:16

In this document, you would learn how to find antibodies for Lipoma

A lipoma is a benign tumor composed of fatty tissue. These are the most common form of soft tissue tumor.

CAUSES:

Genetic studies in mice from the laboratory of Santa J. Ono have shown a correlation between the HMG I-C gene (previously identified as a gene related to obesity) and lipoma development. [1]

Go to uniprot http://www.uniprot.org/ an search for HMG1 .

Select the sequence with the accession number P17096.

Then click on cross references.

Select PDB for protein structure.

PDB:

The Protein Data Bank (PDB) is a repository for the 3-D structural data of large biological molecules, such as proteins and nucleic acids. (See also crystallographic database). The data, typically obtained by X-ray crystallography or NMR spectroscopy and submitted by biologists and biochemists from around the world, are released into the public domain, and can be accessed at no charge on the internet.[2]

Now select Jmol below the image.

Now go back to uniprot cross references.

Click on HGNC

Select GeneCards from the bottom.

GeneCards :

GeneCards® is a searchable, integrated database of human genes that provides concise genomic, proteomic, transcriptomic, genetic and functional information on all known and predicted human genes. Information featured in GeneCards includes orthologies, disease relationships, mutations and SNPs, gene expression, gene function, pathways, protein-protein interactions, related drugs & compounds and direct links to cutting edge research reagents and tools such as antibodies, recombinant proteins, clones, expression assays and RNAi reagents.[3]